Liverpool and Brighton lead the way when it comes to the FA Cup shootout records of the last 32
The Premier League duo boast seven wins from seven between them. Planet Sport looks at how the rest of the fourth-round sides match up.
Manchester United vs Middlesbrough
Manchester United shootouts: 3 (wins 0, losses 3)
Twelve-time FA Cup winners Manchester United will be hoping that penalties are not required at Old Trafford against Chris Wilder's Championship outfit.
Involved in three penalty shootouts, albeit all under the leadership of Sir Alex Ferguson, United have bowed out to Southampton, Everton and Arsenal.
Middlesbrough shootouts: 2 (wins 2, losses 0)
Chelsea vs Plymouth
Chelsea shootouts: 4 (wins 2, losses 2)
Plymouth Argyle shootouts: 0
Kidderminster Harriers vs West Ham United
Kidderminster shootouts (in the FA Cup proper): 0
West Ham United shootouts: 5 (wins 2, losses 3)
Crystal Palace vs Hartlepool United
Crystal Palace shootouts: 0
Hartlepool United shootouts: 1 (wins 1, losses 0)
Huddersfield Town vs Barnsley
Huddersfield shootouts: 0
Barnsley shootouts: 1 (wins: 1, losses 0)
Peterborough United vs QPR
Peterborough shootouts: 3 (wins 1, losses 2)
Queens Park Rangers shootouts: 1 (wins 1, losses 0)
After playing out a 1-1 draw with League One Rotherham, stand-in keeper Jordan Archer pushed Chiedozie Ogbene's penalty around the post to send the Championship side through 8-7.
Southampton vs Coventry City
Southampton shootouts: 2 (wins 1, losses 1)
Coventry City shootouts: 2 (wins 0, losses 2)
Everton vs Brentford
Everton shootouts: 3 (wins 2, losses 1)
Brentford shootouts: 1 (wins 1, losses 0)
Stoke City vs Wigan Athletic
Stoke shootouts: 1 (wins 1, losses 0)
Wigan shootouts: 2 (wins 1, losses 1)
Manchester City vs Fulham
Manchester City shootouts: 0
Fulham shootouts: 2 (wins 1, losses 1)
Wolverhampton Wanderers vs Norwich
Wolves shootouts: 3 (wins 1, losses 2)
Norwich City shootouts: 2 (wins 1, losses 1)
Cambridge United vs Luton Town
Cambridge United shootouts: 1 (wins 0, losses 1)
Luton Town shootouts: 1 (wins 0, losses 1)
Tottenham vs Brighton
Tottenham shootouts: 2 (wins 1, losses 1)
Their defeat came at the hands of Norwich in the fifth round in 2020 when Canaries keeper Tim Krul famously wrote the names of Spurs' spot-kick takers on his water bottle, complete with their predicted way of shooting.
Brighton shootouts: 4 (wins 4, losses 0)
Liverpool vs Cardiff City
Liverpool shootouts: 3 (wins 3, losses 0)
Cardiff shootouts: 1 (wins 0, losses 1)
Nottingham Forest vs Leicester City
Forest shootouts: 0
Leicester City shootouts: 2 (wins 1, losses 1)
Bournemouth vs Boreham Wood
Bournemouth shootouts: 3 (wins 2, losses 1)
Boreham Wood shootouts (in the FA Cup proper): 1 (wins 1, losses 0)
The non-league side defeated then-League Two club Southend United in the first round on penalties last season, goalkeeper Nathan Ashmore proving their hero.