Spurs to march on at Turf Moor, plus five other Wednesday accumulator bets
Tottenham and Leicester should safely negotiate their all-Premier League EFL Cup ties, while Liverpool and Brentford are also fancied to qualify for the quarter-finals.
Burnley vs Tottenham
Sean Dyche's men are still winless but have at least climbed above Norwich and Newcastle at the foot of the Premier League after three draws in their last four games.
Last time out the Clarets drew 2-2 draw at Southampton, with Ivorian winger Maxwel Cornet scoring both goals to make it three in his last four starts, and Cornet looks set to be unleashed once again against a side he was heavily linked with a few years back.
Burnley's home form is a cause for concern as the hosts have not scored in their last two league outings at Turf Moor, but Spurs are not much better on the road, winning just one of their last seven games away from north London in all competitions.
Last time out Tottenham fell to a bitterly disappointing defeat at West Ham, a result made even worse by the fact Nuno Espirito Santo had essentially sacrificed their Europa Conference League match at Vitesse to keep his first teamers fresh.
We're expecting a far stronger team selection from Nuno at Turf Moor in a game that has assumed great importance for a manager starting to look nervously over his shoulder, and while a win would do wonders for Burnley's confidence you have to think Sean Dyche will have one eye on their home game against Brentford next weekend.
Preston vs Liverpool
The Reds' 5-0 demolition of Man United last weekend was a superb statement victory but the Liverpool side that steps out at Deepdale will be a very different one from that memorable afternoon at Old Trafford.
However, if their 3-0 win at Norwich in the last round is anything to go by then Jurgen Klopp's men are worthy favourites against a Preston side lying 19th in the Championship.
Leicester City vs Brighton
Everything is rosier in the garden for Brendan Rodgers and his Leicester side as the Foxes' season finally seems to have taken off after three straight wins in all competitions.
And a visit from a bruised Brighton side trending in the wrong direction is an outstanding opportunity for the hosts to continue that run and advance to the quarter-finals.
Since beating Leicester at the Amex Stadium in September Graham Potter's men have drawn three and lost one of their Premier League outings, scoring just twice and looking a pale imitation of the side that briefly occupied fourth spot just a few weeks ago.
If their last EFL Cup match is anything to go by then it looks like Neal Maupay and Leandro Trossard may have the night off with next weekend's clash with Liverpool in mind, and while Jamie Vardy will be missing for the hosts, they have far more strength in depth.
It all means that the hosts look a cracking price to win in 90 minutes and are a worthy addition to our acca.
Stoke City vs Brentford
Brentford may have taken to life in the Premier League like a duck to water but we're about to find out if they can do it on a cold Wednesday evening in Stoke as they head north for a clash with the Potters.
However, even a rotated Brentford line-up will represent a similar test to the Championship leaders, and with Stoke struggling and set to make changes themselves, we can't see anything other than an away win here.
Hibernian vs Celtic
The match of the night in the Scottish Premiership sees fourth play fifth as Hibernian host Celtic at Easter Road, but the two sides have been heading in opposite directions in the last few weeks.
Rangers vs Aberdeen
The Glasgow double should come in tomorrow as we reckon leaders Rangers will see off Aberdeen and earn a third home win in four league matches.
With Celtic's recent resurgence and Hearts and Dundee United also breathing down their necks, keeping their momentum going is vital for Steven Gerrard's men, and we reckon they will get it done with something to spare, with Rangers -1 our final acca selection.