Bookies appear to write off Chelsea’s title hopes after they suffer Hammer blow
Blues out to 5/1 to win the Premier League as Manchester City and Liverpool leapfrog them in the table.
However, Tuchel's side have now won just two of their last five, and the most recent of those required a late, late winner to see off Watford, a result the German manager described as "lucky".
League leaders at the start of play, Chelsea finished the weekend in third and the bookies reacted by easing their odds on winning the title from 11/4 to 5/1.
And while Chelsea conceded a late goal to go down to the Hammers, Liverpool scored one of their own to see off the challenge of Wolves.
Divock Origi's superb 94th-minute strike wrestled all three points from Molineux to rack up a fourth straight victory for Jurgen Klopp's side.
Manchester City remain favourites, however, with their emphatic 3-1 win over Watford taking them to the Premier League summit for the first time this season.
There was also movement in the top-four betting, with West Ham's second 3-2 victory over one of the top three - they beat Liverpool by the same scoreline in November - seeing them cut to 10/3 to finish inside the Champions League berths.
Tottenham are also 7/2 following their third successive league win under Antonio Conte.
Manchester United remain favourites to grab the fourth spot, however, at 10/11 having eked out a 1-0 win over Crystal Palace in Ralf Rangnick's first game in charge.
At the bottom, there was little movement in the betting despite a Callum Wilson goal earning Newcastle their first win of the campaign.
The Magpies are 8/11 to suffer the drop, with Burnley, the team they beat, 10/11.
Norwich, who lost 3-0 at Tottenham, remain 2/9 favourites to go down.