Premier League champions Manchester City will open their defence against promoted Southampton at the Etihad Stadium on August 18
Runners-up Manchester United head to Goodison Park to face Everton where they’ll want to make an early statement against a side that played a key role in their surrendering of the title.
Roberto Di Matteo’s first match as full-time manager of Chelsea sees the Blues head to Wigan while Arsenal welcome Sunderland to the Emirates.
Whoever takes over the reins at Tottenham will be faced with the tough task of a trip to Newcastle first up.
New Liverpool boss Brendan Rodgers should have a slightly easier opening assignment when the Reds visit West Brom.
Other new bosses Paul Lambert (Aston Villa) and Chris Hughton (Norwich) will have do deal with the challenge of trips to West ham and Fulham respectively.
Opening day fixtures for the 2012/13 season:
Man City v Southampton
Everton v Man United
Arsenal v Sunderland
Newcastle v Tottenham
Wigan v Chelsea
West Brom v Liverpool
QPR v Swansea
West Ham v Aston Villa
Reading v Stoke
Fulham v Norwich